Urinary and Kidney

Blood 01 Jan 2013

A Study of NeoRecormon (Epoetin Beta) in Patients With Renal Anemia

This study will determine whether 8 weekly monitoring of hemoglobin and iron parameters in the correction phase of NeoRecormon therapy in patients with renal anemia is as safe and effective as 4 weekly monitoring. Patients with chronic kidney disease will receive NeoRecormon at a dose aimed at achieving and maintaining…
Research and Trials 01 Jan 2013

Short Term Effects of FX Dialysers on QOL and Inflammation

This study aims to assess the short-term effects of the FX-class Dialyser on quality of life and inflammatory markers in stable haemodialysis patients with chronic kidney failure. Official Title Short-Term Effects of the FX-Class of Haemodialyser on Quality of Life and Inflammatory Markers in Stable Dialysis Patients. Conditions Kidney Failure,…
Lungs 01 Jan 2013

A Study of LY2127399 in Patients with Systemic Lupus Erythematosus

The purpose of this SLE study is to evaluate the efficacy, safety and tolerability of two different doses of LY2127399 administered in addition to standard of care therapy in patients with active SLE. Official Title A Phase 3, Multicenter, Randomised, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of…
Study The Effects Of Different Doses Of UK-369,003 In Men With Overactive Bladder.
Men's Health 01 Jan 2013

Study The Effects Of Different Doses Of UK-369,003 In Men With Overactive Bladder.

This is a 12 week study in which different doses of UK-369,003 will be administered to patients with a diagnosis of overactive bladder. Patients will complete a series of questionnaires before treatment, during treatment and after treatment, to assess whether UK-369,003 has improved their symptoms of overactive bladder and erectile…
Blood 01 Jan 2013

A Prospective, Surveillance Study to Estimate the Incidence of Pure Red Blood Cell Aplasia (Aplastic Anemia) Mediated by Erythropoietin Antibodies Among Patients With Chronic Kidney Failure and Subcutaneous Exposure to Recombinant Erythropoietin Prod

The purpose of this study is to estimate the incidence rate of pure red cell aplasia (PRCA; aplastic anemia) mediated by erythropoietin (EPO) antibodies in patients who are receiving subcutaneous (s.c.) EPREX (polysorbate 80 formulation) for the treatment of anemia associated with chronic renal failure (CRF), and to compare this…
Research and Trials 01 Jan 2013

Incident Dialysis

Randomised trial to evaluate the efficacy and safety of Cinacalcet treatment in combination with low dose vitamin D for the treatment of subjects with secondary…
Cancer 01 Jan 2013

GW786034 In Subjects With Locally Recurrent Or Metastatic Clear Cell Renal Cell Carcinoma

Phase II, multi-center, two-stage study utilising a randomised discontinuation design to evaluate the safety and efficacy of GW786034 in adult subjects with locally recurrent or metastatic clear-cell Renal Cell Carcinoma (RCC). Official Title A Phase II Study of GW786034 Using a Randomised Discontinuation Design in Subjects With Locally Recurrent or…
Research and Trials 01 Jan 2013

Augmented Vs. Normal Renal Replacement Therapy in Severe Acute Renal Failure (ARF)

This study seeks to determine if increasing the dose of continuous renal replacement therapy (CRRT) reduces 90-day all cause mortality in Intensive Care Unit (ICU) patients with severe acute renal failure (ARF). Official Title Multicentre, Unblinded, Open Label, Randomised, Controlled Trial to Assess the Effect of Augmented Vs. Normal Continuous…
Heart 01 Jan 2013

The Effect of Atorvastatin on Postoperative Renal Function After Cardiac Surgery

Atorvastatin might reduce the oxidative stress that occurs during cardiopulmonary bypass, and thus, prevent or reduce the magnitude of acute kidney dysfunction in those patients…