Research and Trials

ICON8: An international phase III randomised trial of dose-fractionated chemotherapy compared to standard three-weekly chemotherapy, following immediate primary surgery or as part of delayed primary surgery, for women with newly diagnosed epithelial ovarian, fallopian tube or primary peritoneal cancer
Cancer 04 Jul 2014

ICON8: An international phase III randomised trial of dose-fractionated chemotherapy compared to standard three-weekly chemotherapy, following immediate primary surgery or as part of delayed primary surgery, for women with newly diagnosed epithelial ovarian, fallopian tube or primary peritoneal cancer

Short title ICON8 (Australia New Zealand Gynaecological Oncology Group trial number ANZGOG14) Summary ICON8 is a randomised (1:1:1 ratio), three-arm, three stage Gynaecologic Cancer InterGroup (GCIG) phase III trial designed to evaluate the safety and efficacy of dose-dense, dose-fractionated carboplatin-paclitaxel chemotherapy in the first-line treatment of ovarian cancer. Official title…
Bone 01 Jan 2013

Effects of Arzoxifene on Bone Fractures and Incidence of Breast Cancer

The purpose of this trial is to study: – Effects of arzoxifene on bone fractures and bone mass. – Effects of arzoxifene on getting breast cancer. – Effects of arzoxifene on certain types of cardiovascular events, such as heart attack and stroke. – Effects of arzoxifene that…
Blood 01 Jan 2013

Severe Hemophilia A Study

To characterize the safety and efficacy of ReFacto AF in treating acute bleeding episodes during prophylaxis treatment, including neoantigenicity. Official Title An Open-label Study to Characterize the Safety and Efficacy of BDDrFVIII Manufactured by the Albumin Free Process (ReFacto AF) in the Treatment of Previously Treated Patients (PTP) with Severe…
A safety and efficacy trial evaluating the use of SanOrg34006 compared to warfarin or acenocoumarol in patients with atrial fibrillation
Heart 01 Jan 2013

A safety and efficacy trial evaluating the use of SanOrg34006 compared to warfarin or acenocoumarol in patients with atrial fibrillation

This trial will include patients who have a heart condition called atrial fibrillation. Atrial fibrillation is an abnormal rhythm (irregular beat) in the heart. Patients with atrial fibrillation have an increased chance for a blood clot to form in the heart and move to other blood vessels in the body…
Bone 01 Jan 2013

dnaJ Peptide for Relieving Rheumatoid Arthritis

A small protein called dnaJ peptide may help people with rheumatoid arthritis (RA) by preventing their immune system cells from attacking their own tissues. The purpose of this study is to determine if small amounts of dnaJ peptide can “re-educate” immune cells in people with RA so that the cells…
Behavioral Treatment, Drug Treatment, and Combined Treatment for Attention Deficit Hyperactivity Disorder (ADHD)
Mental Health 01 Jan 2013

Behavioral Treatment, Drug Treatment, and Combined Treatment for Attention Deficit Hyperactivity Disorder (ADHD)

The purpose of this study is to determine the effectiveness of behavioral treatment, drug treatment, and combined treatment for children with Attention Deficit Hyperactivity Disorder (ADHD). This study will also examine the interactions between different levels of behavioral and drug treatments. Official Title ADHD Treatment: Comparative and Combined Dosage Effects…
Nasal Irritation Study
Lungs 01 Jan 2013

Nasal Irritation Study

This study seeks to document differences in nasal irritant sensitivity within the population. We are interested in knowing whether age, gender, and allergy status (nasal allergies) predict nasal irritant sensitivity. This is important in understanding symptom reporting patterns in air pollution situations (particularly in so-called “problem buildings”), as well as…
Preventing the Recurrence of Depression with Drugs and Psychotherapy
Mental Health 01 Jan 2013

Preventing the Recurrence of Depression with Drugs and Psychotherapy

The purpose of this study is to determine whether the addition of Cognitive Therapy (CT) to antidepressant medication (ADM) enhances treatment for depression. This study will also test whether the addition of CT to ADM will prevent recurrences of depression after therapy is over. Official Title Prevention of Recurrence in…
Gastro 01 Jan 2013

Genetic Linkage Study for Hereditary Pancreatitis

OBJECTIVES: Establish linkage in families with hereditary pancreatitis between the phenotype and a chromosomal locus (loci) that contains the responsible gene. Official Title – Pancreatitis Conditions Study Type Observational Study Design Natural History Further Details PROTOCOL OUTLINE: This is a genetics study. Blood samples are collected from patients…