Research and Trials

Cancer 04 Jul 2014

ICON8: An international phase III randomised trial of dose-fractionated chemotherapy compared to standard three-weekly chemotherapy, following immediate primary surgery or as part of delayed primary surgery, for women with newly diagnosed epithelial ovarian, fallopian tube or primary peritoneal cancer

Short title ICON8 (Australia New Zealand Gynaecological Oncology Group trial number ANZGOG14) Summary ICON8 is a randomised (1:1:1 ratio), three-arm, three stage Gynaecologic Cancer InterGroup (GCIG) phase III trial designed to evaluate the safety and efficacy of dose-dense, dose-fractionated carboplatin-paclitaxel chemotherapy in the first-line treatment of ovarian cancer. Official title…

Cancer 01 Jan 2013

“REDUCE” – A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased Risk

Purpose This 4-year study will compare how safe and effective an oral investigational medicine is (compared to placebo) in preventing the development of prostate cancer in men that are defined by the study entrance criteria as being at an increased risk for prostate cancer. Study visits to the clinic…

Blood 01 Jan 2013

Aggressive vs. conservative red blood cell transfusion therapy in surgical patients with Cardiovascular Disease

Purpose: To compare aggressive with conservative red blood cell transfusion therapy in surgical patients with cardiovascular disease. Official Title Conditions – Anemia- Blood Disease- Blood Transfusion- Cardiovascular Diseases- Heart Diseases- Myocardial Infarction- Thromboembolism- Pneumonia- Cerebrovascular Accident Study Type Interventional Study Design Preventional, Randomised. Further Details BACKGROUND: Red blood cell…

Heart 01 Jan 2013

RAPPORT

The benefit of catheter-based reperfusion for acute myocardial infarction (MI) is limited by a 5 % to 15 % incidence of in-hospital major ischemic events, usually caused by infarct artery reocclusion, and a 20 % to 40 % need for repeat percutaneous or surgical revascularization. Platelets play a key role…

Chronic Pain 01 Jan 2013

Migraine and Healthy Eyes Research Project

Volunteers are invited to participate in a research study assessing the effects of migraine headaches on visual function (HREC#0932638). The study will involve up to three test sessions, each of which may take up to three hours. During the sessions, the following will be performed:An eye examination to determine whether you are eligible to…

Research and Trials 01 Jan 2013

Epstein-Barr Virus (EBV)-Specific T Cells as Therapy for Relapsed/Refractory EBV-Positive Lymphomas (EPL)

This trial will use a new method of treating lymphoma using a therapy derived from a person's Killer T cells.

Cancer 01 Jan 2013

Lume Lung 2: BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC

The trial will be performed to evaluate if BIBF 1120 in combination with standard pemetrexed therapy is more effective than placebo plus standard pemetrexed therapy…

Research and Trials 01 Jan 2013

Kidney Stone Structural Analysis By Helical Computed Tomography (CT)

Current practices of the diagnosis of urinary stones gives little information on the probable fragility of stones using shock wave lithotripsy (SWL), and many patients receive more SW’s than is necessary to break up their stones. Indeed, some patients are treated with SWL when their stones cannot be fragmented using…

Chronic Pain 01 Jan 2013

Intra-Articular Injection of Botulinum Toxin Type A for Shoulder Pain

The purpose of this study is to determine whether intra-articular botulinum toxin type A is effective in the treatment of chronic joint pain. Official Title Intra-Articular Injection of Botulinum Toxin Type A for the Treatment of Shoulder Pain: A Randomized, Double Blinded, Placebo Controlled Trial. Conditions Arthritis Shoulder…