Research and Trials

Cancer 04 Jul 2014

ICON8: An international phase III randomised trial of dose-fractionated chemotherapy compared to standard three-weekly chemotherapy, following immediate primary surgery or as part of delayed primary surgery, for women with newly diagnosed epithelial ovarian, fallopian tube or primary peritoneal cancer

Short title ICON8 (Australia New Zealand Gynaecological Oncology Group trial number ANZGOG14) Summary ICON8 is a randomised (1:1:1 ratio), three-arm, three stage Gynaecologic Cancer InterGroup (GCIG) phase III trial designed to evaluate the safety and efficacy of dose-dense, dose-fractionated carboplatin-paclitaxel chemotherapy in the first-line treatment of ovarian cancer. Official title…

Chronic Pain 01 Jan 2013

Migraine and Healthy Eyes Research Project

Volunteers are invited to participate in a research study assessing the effects of migraine headaches on visual function (HREC#0932638). The study will involve up to three test sessions, each of which may take up to three hours. During the sessions, the following will be performed:An eye examination to determine whether you are eligible to…

Research and Trials 01 Jan 2013

Epstein-Barr Virus (EBV)-Specific T Cells as Therapy for Relapsed/Refractory EBV-Positive Lymphomas (EPL)

This trial will use a new method of treating lymphoma using a therapy derived from a person's Killer T cells.

Cancer 01 Jan 2013

Lume Lung 2: BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC

The trial will be performed to evaluate if BIBF 1120 in combination with standard pemetrexed therapy is more effective than placebo plus standard pemetrexed therapy…

Research and Trials 01 Jan 2013

Kidney Stone Structural Analysis By Helical Computed Tomography (CT)

Current practices of the diagnosis of urinary stones gives little information on the probable fragility of stones using shock wave lithotripsy (SWL), and many patients receive more SW’s than is necessary to break up their stones. Indeed, some patients are treated with SWL when their stones cannot be fragmented using…

Chronic Pain 01 Jan 2013

Intra-Articular Injection of Botulinum Toxin Type A for Shoulder Pain

The purpose of this study is to determine whether intra-articular botulinum toxin type A is effective in the treatment of chronic joint pain. Official Title Intra-Articular Injection of Botulinum Toxin Type A for the Treatment of Shoulder Pain: A Randomized, Double Blinded, Placebo Controlled Trial. Conditions Arthritis Shoulder…

Hormones 01 Jan 2013

Ghrelin, Growth Hormone and Cortisol Interaction in Growth Hormone Deficient Patients

In growth hormone deficient patients: Determination of endogenous circulating ghrelin levels, ghrelin effects on insulin sensitivity, appetite, energy metabolism, and signal transduction in fat and muscle. Official Title Effects of Acute Ghrelin Infusion to Growth Hormone Deficient Adults: Growth Hormone and Cortisol Interaction. Conditions  Hypopituitarism Study Type Interventional Study…

Gastro 01 Jan 2013

Truvada Versus Truvada Plus HBIG in Prevention of Chronic Hepatitis B Recurrence Post Liver Transplant

The objective of this study is to evaluate the safety and antiviral efficacy of the combination therapy (emtricitabine/tenofovir disoproxil fumarate), plus or minus Hepatitis B Immunoglobulin (HBIG) in preventing the recurrence of chronic hepatitis B after a patient (who was chronically infected with hepatitis B pre-liver transplant) has undergone a…

Heart 01 Jan 2013

Angiotensin II Receptor Blockers (ARB) and ACE Inhibitors (ACEI) on Silent Brain Infarction and Cognitive Decline

The purpose of this study is to elucidate whether or not angiotensin II receptor blockers (ARB) are more beneficial or equal to angiotensin converting enzyme inhibitors (ACEI) on development or progression of silent brain infarction and cognitive decline in Japanese patients with essential hypertension in the elderly. Official Title Effects…