Objective:Assess the efficacy of a single infusion of a high titer pertussis immune globulin for the treatment of severe pertussis in children.

Official Title


  • Pertussis
  • Whooping Cough

Study Type


Study Design

Treatment, Randomized.

Further Details

Protocol Outline: This is a randomized, multicentre study. Patients are randomized to receive an infusion of either pertussis immune globulin or placebo (0.9% saline).

Patients are followed every 2 weeks for up to 6 months.

Study Start

August 1997

Eligibility & Criteria


  • Ages Eligible for Study: up to 5 Years
  • Genders Eligible for Study: Both
  • Accepts Healthy Volunteers: No

Inclusion Criteria:

  • Documented infection with Bordetella pertussis

Total Enrolment


Contact Details

Scott A. Halperin
IWK Health Centre




IWK Health Centre