The purpose of the research is to study the effects of two different injection therapies for the treatment of lateral epicondylitis (tennis elbow). Specifically, we will look at which therapy provides better short and long-term relief of pain, which treatment allows better function and less disability, and which treatment gives back better strength in the affected hand. Each subject will receive only one of the two treatments. Although both of these treatments are usually very well tolerated, it is important to make this comparison because it is believed that one of these therapies may have better long term effectiveness, with a lower cost, and smaller number of potential side effects.
Prolotherapy vs. Corticosteroid Therapy for the Treatment of Lateral Epicondylitis of the Elbow, A Randomized Controlled Trial.
- Lateral Epicondylitis
Treatment, Randomised, Double-Blind, Active Control, Single Group Assignment, Efficacy Study.
Primary Outcome Measures:
- 10 cm Visual Analogue Scale (VAS)
- Disabilities of the Arm, Shoulder, and Hand (DASH)
Secondary Outcome Measures:
- Grip Strength
Eligibility & Criteria
- Ages Eligible for Study: 18 Years to 75 Years
- Genders Eligible for Study: Both
- Accepts Healthy Volunteers: Yes
- Age criteria >18yo, <75yo, history of pain > 3 months, < 2 years; pain on resisted extension of wrist and/or middle finger test, (resisted extension of middle finger at the MCP joint)
- Local tenderness to palpation at the lateral epicondyle
- Subject can read and write in English.
- History of steroid injections within 6 months prior to intervention;
- Other arm/forearm pathology such as radial nerve compression; pregnancy/nursing;
- Known thrombocytopenia, coagulopathy, or bleeding diathesis; history of diffuse pain syndrome;
- History of Inflammatory Arthropathy;
- Workman’s Compensation (RSI) > 2 years; patients with litigation pending/planned; patients who are unable to return for F/U;
- Intolerance/allergy to local anesthetics or injection corticosteroids; fear of needles; untreated depression;
- History of narcotic use for pain management greater than 1 month or history of narcotic abuse problem.
Joanne Borg-Stein, MD
Alexios Carayannopoulos, DO, MPH
Spaulding Rehabilitation Hospital
Wellesley Outpatient Center
United States, 02481