The purpose of this trial is to study:

– Effects of arzoxifene on bone fractures and bone mass.
– Effects of arzoxifene on getting breast cancer.
– Effects of arzoxifene on certain types of cardiovascular events, such as heart attack and stroke.
– Effects of arzoxifene that changes the amount of certain substances in the blood that are related to osteoporosis and cardiovascular health.
– Effects of arzoxifene on the uterus.
– The safety of arzoxifene and any side effects.

Official Title

Effects of Arzoxifene on Bone Fractures and Incidence of Breast Cancer


Osteoporosis, Postmenopausal

Study Type


Study Design

Treatment, Safety/Efficacy Study

Further Details

Study Start

July 19, 2004

Eligibility & Criteria

Inclusion Criteria:- 60-85 years of age – Female – At least two years since last menstrual cycle Exclusion Criteria:- Abnormal or unexplained vaginal bleeding. – Bone disorders, other than osteoporosis or low bone mass – History of breast cancer, cancer of the uterus, or any cancer in the last five years (except skin cancer). – History of cerebral vascular accidents or venous thromboembolic events – Medications outlined

Total Enrolment

Contact Details

Recruitment and information available at a number of Australian centers, please call, for additional information regarding investigative sites for this trial, 1-877-285-4559.