This study is being carried out to see if ZD4054 is effective in treating prostate cancer and spread of cancer to the bone, and if so, how it compares with placebo (sugar pill). The study will also provide further information on the safety of ZD4054.

Official Title

Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multi-Centre Study to Assess ZD4054 in Pain-Free or Mildly Symptomatic Patients With Prostate Cancer and Bone Metastases Who Have Rising Serum Prostate Specific Antigen (PSA)

Conditions

Study Type

Interventional

Study Design

Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study

Further Details

Study Start

August 2004

Eligibility & Criteria

Ages Eligible for Study: 18 Years and aboveGenders Eligible for Study: Male CriteriaInclusion Criteria:- Surgically or medically castrated – Bone metastasis – Rising PSA Exclusion Criteria:- Opiate use – Prior chemotherapy

Total Enrolment

260

Contact Details

AustraliaResearch Site, Nedlands, Australia; Recruiting Australia, QueenslandResearch Site, Wolloongabba, Queensland, Australia; Not yet recruiting Australia, South AustraliaResearch Site, Ashford, South Australia, Australia; Recruiting Australia, VictoriaResearch Site, Wodonga, Victoria, Australia; Recruiting