Research and Trials

Research and Trials 01 Jan 2013

Safety, Tolerability and Pharmacokinetics of Multiple Doses of ZGN-433 in Obese Female Volunteers

   
Research and Trials 01 Jan 2013

The CANTATA-MSU Trial (CANagliflozin Treatment and Trial Analysis – Metformin and SUlphonylurea)

The purpose of this study is to evaluate the efficacy and safety of 2 different doses of canagliflozin compared with placebo in patients with type 2 diabetes mellitus who are receiving treatment with metformin and sulphonylurea and have inadequate glycemic (blood sugar) control. Official Title A Randomized, Double-Blind, Placebo-Controlled, 3-Arm,…
Safety and Efficacy of GS-9350-boosted Atazanavir Versus Ritonavir-boosted Atazanavir in HIV-1 Infected Adults
Research and Trials 01 Jan 2013

Safety and Efficacy of GS-9350-boosted Atazanavir Versus Ritonavir-boosted Atazanavir in HIV-1 Infected Adults

To evaluate the safety and efficacy of a regimen containing GS-9350-boosted atazanavir plus emtricitabine/tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus emtricitabine/tenofovir disoproxil fumarate in HIV 1 infected, antiretroviral treatment-naïve adults. Development of GS-9350 as a "pharmacoenhancer" could provide a beneficial alternative to ritonavir for use in combination with protease inhibitors.
Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial (ARISE)
Research and Trials 01 Jan 2013

Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial (ARISE)

EGDT, compared to standard Australasian resuscitation practice, reduces 90-day all-cause mortality in patients presenting to the ED with severe sepsis.
Radiotherapy for Neurotropic Melanoma of the Head and Neck (RTN2)
Cancer 01 Jan 2013

Radiotherapy for Neurotropic Melanoma of the Head and Neck (RTN2)

Melanoma is a serious and common malignancy in Australia. It is the third most common cancer in Australia and approximately 1000 Australians will die of…
Randomised, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF (ARTEMIS)
Lungs 01 Jan 2013

Randomised, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF (ARTEMIS)

The ARTEMIS-IPF study is for people who have been diagnosed with IPF and are between 40 and 80 years of age. People who have been…
Research and Trials 01 Jan 2013

Epstein-Barr Virus (EBV)-Specific T Cells as Therapy for Relapsed/Refractory EBV-Positive Lymphomas (EPL)

This trial will use a new method of treating lymphoma using a therapy derived from a person's Killer T cells.
Research and Trials 01 Jan 2013

Incident Dialysis

Randomised trial to evaluate the efficacy and safety of Cinacalcet treatment in combination with low dose vitamin D for the treatment of subjects with secondary…
Research and Trials 01 Jan 2013

The Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy Trial (STABILITY)

This study will test whether darapladib can safely lower the chances of having a cardiovascular event in people with coronary heart disease.