This study will determine if NXY-059 is safe in patients with an acute stroke caused by bleeding in the central nervous system.

Official Title

CHANT (Cerebral Hemorrhage And NXY Treatment) A Double-Blind, Randomized, Placebo-Controlled, Parallel group, Multicenter, Phase IIb Study to Assess the Safety and Tolerability of Intravenous Infusion of NXY-059 in Adult Patients with Acute Intracerebral Hemorrhage (ICH)


Intracerebral Hemorrhage

Study Type


Study Design

Treatment, Randomized, Double-Blind, Placebo Control, Factorial Assignment, Safety Study

Further Details

Study Start

Eligibility & Criteria

Inclusion Criteria:- Males and females – Intracerebral Hemorrhage as the cause of stroke symptoms – Onset of symptoms within 6 hours – Full functional independence prior to the present stroke Exclusion Criteria:- Unconsciousness – Subjects who are unlikely to complete the infusion of investigational product and/or are unlikely to undergo active medical management during that period due to a severe clinical condition. – Severe illness with life expectancy less than 6 months. – Known severe kidney disorder. – Current known alcohol or illicit drug abuse or dependence. – Pregnant or breast-feeding. – Treatment with acetazolamide and methotrexate is not permitted during the infusion – Participation in a previous clinical study within 7 days. – Meets all other exclusion criteria

Total Enrolment

Contact Details

This study is not yet recruiting please visit for further details and contact information.

All content and media on the HealthEngine Blog is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice. Always seek the guidance of your doctor or other qualified health professional with any questions you may have regarding your health or a medical condition. Never disregard the advice of a medical professional, or delay in seeking it because of something you have read on this Website. If you think you may have a medical emergency, call your doctor, go to the nearest hospital emergency department, or call the emergency services immediately.