Triplo-X syndrome is a genetic disorder. It occurs when the sperm fertilises an egg that has an extra X chromosome (a sex gene) due to non-disjunction. Triplo-X results when the sperm brings an X chromosome. The person will be an infertile female with some mild cognitive impairment.

If the sperm was to bring a  Y chromosome the embryo would contain two X chromosomes and one Y and would develop a condition called Klinefelter syndrome.

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