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Lipase Test

Lipase is an enzyme produced by the pancreas. It is usually used to confirm or exclude a diagnosis of pancreatitis.

How the Test is Performed

The Lipase test requires a few millilitres of blood from a vein.

Medical Conditions and Symptoms

Abdominal pain, particularly in the epigastric region (upper abdomen) and radiating (going through) to the back, may be an indication of pancreatitis - inflammation of the pancreas. Major risk factors for this disease are gallstones and excessive alcohol intake.

Test Results Explained

A markedly elevated level of lipase in the bloodstream (the enzyme can also be tested for in urine but this is rarely performed) almost certainly indicates a diagnosis of pancreatitis (inflamation of the pancreas). A normal level may sometimes be seen in a flare-up of chronic pancreatitis, when the pancreas is so severely damaged from previous episodes of inflammation that there is insufficient pancreatic tissue to raise the enzyme level in the blood.

Related Specialists

  • General Practitioner (GP)
  • Gastroenterologist
  • Hepatologist
  • General Surgeon
  • Emergency Physician
  • General Physician

Related Procedures

  • Endoscopic Retrograde Cholangiopancreatography (ERCP)

Related Tests

  • Amylase
  • Liver Function Tests (LFT)
  • Abdominal CT scan
  • Abdominal Ultrasound scan

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